First Line Therapy in 2014

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First Line Therapy in 2014

The choice of antiretroviral therapy for those naïve to therapy is vast, with over 30 drugs available for the treatment of HIV disease. Although international and national guidelines often give recommended preferred choices for commencement of therapy, it is important that treatment is always individualised. Therefore for the individual patient, it may be necessary to utilise treatments outside...

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First-line and second-line antiretroviral therapy.

January, 2004, administration of measles vaccine was recommended between 12 and 24 months of age, instead of between 12 and 15 months when children have the greatest risk of contracting measles. There is no established system to check vaccination status on entry to the school systems. Strong political and social desire has to be inspired, and vigorous educational campaigns for policy makers and...

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Association of First-Line and Second-Line Antiretroviral Therapy Adherence

BACKGROUND Adherence to first-line antiretroviral therapy (ART) may be an important indicator of adherence to second-line ART. Evaluating this relationship may be critical to identify patients at high risk for second-line failure, thereby exhausting their treatment options, and to intervene and improve patient outcomes. METHODS Adolescents and adults (n = 436) receiving second-line ART were a...

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Atrial Fibrillation Ablation: First-Line Therapy?

Background: Ablation for atrial fibrillation (AF) is a widely-accepted treatment for this arrhythmia. Ablation is traditionally reserved for second-line therapy in patients who have failed drug therapy, but it may be ready for first-line treatment. Objective: This article outlines the rationale for using ablation as first-line therapy for AF. Findings: AF increases both morbidity and mortality....

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First line therapy for metastatic pancreatic cancer.

Metastatic pancreatic cancer remains a difficult disease to treat; however, there are more new drug combinations on the horizon each week. We will discuss the results of the MPACT trial presented at the 2013 ASCO Annual Meeting (Abstracts #4005, #4058, and #4059) and compare to the 2011 FOLFIRINOX data.

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ژورنال

عنوان ژورنال: BMC Infectious Diseases

سال: 2014

ISSN: 1471-2334

DOI: 10.1186/1471-2334-14-s2-s3